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Stroke and TIA: FAST Recognition and Urgent Referral

Every stroke symptom is a 999 call: recognise FAST, act immediately, and never give aspirin in the pharmacy before hospital assessment.

Why this matters

Stroke is one of the leading causes of death and disability in the UK, with around 100,000 strokes and 50,000 transient ischaemic attacks (TIAs) occurring each year in England. In both cases, speed is the single most important factor in outcome. For ischaemic stroke, which accounts for around 85% of all strokes, thrombolysis can be given within 4.5 hours of symptom onset and mechanical thrombectomy within 24 hours in selected patients. Every minute without treatment, approximately 1.9 million neurones are lost.

Community pharmacists are a trusted frontline point of contact. A patient or carer describing a "funny turn", sudden weakness, or slurred speech may not realise they are describing a stroke or TIA. Recognising the signs, acting without delay, and avoiding common pitfalls (particularly giving aspirin in the pharmacy before imaging) can determine whether a patient makes a full recovery or is left with permanent disability. A TIA with fully resolved symptoms is not a reason for reassurance: the risk of a full stroke within 48 hours can be as high as 10%, making same-day emergency assessment essential.

Red flags vs more likely benign

FeatureMore likely benignRed flag ⚠
Facial symmetrySymmetrical smile, equal facial movementSudden facial drooping or asymmetry on smiling: possible stroke
Arm strengthBoth arms raised equally, no drift over 10 secondsOne arm drifts down or cannot be raised when tested simultaneously
SpeechClear articulation, coherent, appropriate wordsSudden slurring, garbled speech, wrong words, or inability to speak
HeadacheGradual-onset tension headache or known migraine patternSudden thunderclap headache: worst ever, no warning; possible haemorrhagic stroke
VisionNormal in both eyes, no new disturbanceSudden loss of vision in one or both eyes, double vision, or loss of visual field
BalanceSteady gait, normal coordinationSudden ataxia, loss of balance, or vertigo combined with any other FAST feature
DurationBrief dizziness or lightheadedness with clear causeNeurological symptoms that resolved fully: possible TIA; still a medical emergency
ConsciousnessAlert, orientated, behaving normallySudden confusion, altered consciousness, or collapse of no apparent cause

What to do in pharmacy

Call 999 immediately for any FAST-positive feature: facial drooping, arm weakness, speech difficulty, or sudden severe headache, vision loss, or loss of consciousness. Do not wait to see if symptoms improve. Note the exact time the symptoms started and relay this clearly to the ambulance crew: it determines eligibility for thrombolysis. Do not give aspirin in the pharmacy before hospital assessment. NICE NG128 does recommend 300mg aspirin for acute ischaemic stroke, but only after CT imaging has confirmed that haemorrhagic stroke has been excluded. In the pre-hospital setting, stroke type cannot be determined without imaging: around 15% of strokes are haemorrhagic, and aspirin worsens outcomes in these patients. If the patient asks whether they should take aspirin, advise them not to in the pharmacy and to call 999 immediately.
If the patient describes neurological symptoms that have now fully resolved (facial droop, arm weakness, speech difficulty, vision loss, or sudden severe headache), treat this as a medical emergency even though the symptoms are gone. Call 999 or direct the patient immediately to the emergency department. Do not advise a routine GP appointment, reassure the patient, or suggest waiting. The risk of a full stroke within the first 48 hours following a TIA is up to 10%, and urgent specialist assessment (including brain imaging, carotid assessment, and antiplatelet initiation after haemorrhage is excluded) can prevent it. Every hour of delay increases that risk.
There is no safe self-care pathway for active or recently resolved stroke or TIA symptoms. The pharmacy role in stroke is secondary prevention: check that patients with known atrial fibrillation are taking their anticoagulant as prescribed and have not stopped it due to a minor bleed or confusion about directions. Offer opportunistic blood pressure monitoring, as hypertension is the single largest modifiable stroke risk factor. Provide smoking cessation support: smokers have roughly twice the stroke risk of non-smokers. Patients already established on antiplatelet therapy (aspirin or clopidogrel) following a previous TIA or stroke should be reminded not to stop it without medical advice.

Key takeaways

  • Any FAST-positive symptom is a 999 call without exception: do not wait to see if it resolves.
  • A TIA with fully resolved symptoms is still a medical emergency: the 48-hour stroke risk is up to 10%.
  • Do not give aspirin in the pharmacy before hospital imaging: NICE NG128 recommends 300mg aspirin for ischaemic stroke, but only after CT imaging excludes haemorrhage; around 15% of strokes are haemorrhagic and aspirin worsens them.

Download the checklist

Download the one-page pharmacy checklist

Professional disclaimer: This article is for educational purposes to support healthcare professionals' clinical decision-making. It does not replace independent professional judgement, local pathways, NICE guidance, or standard medical literature. Members of the public must not use this resource for self-diagnosis and should seek prompt advice from a qualified healthcare professional if experiencing chest pain, palpitations, fainting, or breathlessness.